October 22, 2021

Science

The world of science and technology

What Your Family History Can’t Tell You

2 min read

What Your Family History Can’t Tell You

Thanks to the National Human Genome Research Institute for supporting this episode. If you’re interested in learning more about the human genome and the latest in polygenic risk score research, head to http://genome.gov/PRS

#polygenicriskscores #science

The first time you visit a new doctor, they’ll probably ask you about your family history – but it turns out that family history doesn’t tell you everything about the risks that can be hidden in your genes.

Hosted by: Hank Green

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Sources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987426/
https://academic.oup.com/hmg/article/23/22/6112/2900819
https://www.broadinstitute.org/news/depth-polygenic-risk-scoring
https://www.nature.com/articles/s41588-018-0183-z
https://jamanetwork.com/journals/jama/article-abstract/2730627
https://www.bmj.com/content/360/bmj.j5757
https://www.nature.com/articles/s41576-018-0018-x
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309089/
https://www.genome.gov/about-genomics/fact-sheets/Genome-Wide-Association-Studies-Fact-Sheet

Image Sources:
https://commons.wikimedia.org/wiki/File:PBB_Protein_BRCA2_image.jpg
https://commons.wikimedia.org/wiki/File:Protein_BRCA1_PDB_1jm7.png
https://commons.wikimedia.org/wiki/File:Manhattan_Plot.png
https://commons.wikimedia.org/wiki/File:Dna-SNP.svg